Mitochondria plays an essential role in regulating cellular metabolic homeostasis, proliferation/differentiation, and cell death. Mitochondrial dysfunction is implicated in many age-related pathologies. Evidence supports that the dysfunction of mitochondria and the decline of mitochondrial DNA copy number negatively affect ovarian aging.

When the human body ages or is subjected to various harmful stimuli, excessive production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) can disrupt the antioxidant defense barrier, triggering cellular oxidative stress (OS) response.

The emergence of mitochondrial OS may be a mechanism leading to infertility, which is not unfamiliar to us. The high OS level detected in the human ovary is associated with follicular atresia, low fertilization potential of oocyte, the risk of aneuploidy, and sub-fertility.

Mitochondria Activity Infusion