Platelet-rich plasma (PRP)

PRP Therapy at LaVida: Platelet-Rich Plasma for Fertility Enhancement

The process of injecting PRP (Platelet-Rich Plasma) into the endometrium aims to increase the thickness of the endometrium, thereby improving the success rate of embryo implantation. During the IVF (In Vitro Fertilization) process, PRP injections can be administered up to three times before starting the use of progesterone medications. Below are the detailed steps for injecting PRP into the endometrium:
ENDOMETRIUM PRP:
Steps for PRP Injection into the Endometrium
1
Pre-injection Preparation:
  • The patient needs to undergo a health check and blood tests to ensure their body is suitable for PRP injection.
  • According to the doctor's advice, fasting or discontinuing certain medications may be required.
2
Blood Collection:
  • The doctor will collect approximately 10-20 milliliters of blood from the patient.
  • The collected blood will be separated using a centrifuge to extract platelet-rich plasma.
3
Preparation of PRP:
  • The platelet-rich plasma will be separated and prepared for injection.
  • PRP will be placed into a clean, sterile syringe.
4
PRP Injection:
  • PRP injections are usually administered during the phase when the endometrium is prepared for embryo implantation.
  • The doctor will use special instruments to inject PRP into the endometrium, typically through the vagina and uterus.
  • PRP helps to increase the thickness of the endometrium, making it more suitable for receiving and supporting the implantation of the embryo.
5
Post-injection Monitoring and Recovery:
  • After the injection, the patient will be monitored to prevent infections or other complications.
  • The patient may experience slight discomfort or minor bleeding, but recovery is usually quick.
6
PRP Administration before Progesterone Use:
  • PRP injections can be administered up to three times before starting the use of progesterone medications.
  • Progesterone medications will be used to further promote the preparation of the endometrium, enhancing the chances of successful embryo implantation.
7
Combined Use with IVF:
  • PRP injections are typically used in conjunction with the IVF process, administered during the preparation phase for embryo implantation to increase the chances of successful implantation and development.
The purpose of PRP injection into the endometrium is to increase the thickness of the endometrium, helping to prepare it for embryo implantation. Up to three PRP injections can be administered before starting progesterone medications. This process should be carried out under the guidance of a professional doctor to ensure the best and safest results.
Ovarian PRP
Ovarian PRP, also known as Ovarian Rejuvenation, involves stimulating the ovaries to enhance follicle development and improve egg quality for fertilization. This technique uses platelet-rich plasma (PRP), which is a concentrated mixture of growth factors and cytokines derived from a woman's own blood. PRP is rich in growth factors that are crucial for tissue regeneration and repair.

The process involves injecting PRP into the ovaries, where it releases growth factors that can:
1. Promote Cellular Rejuvenation:
Stimulate the repair and regeneration of ovarian tissues.
2. Increase Ovarian Blood Flow:
Enhance the delivery of oxygen and nutrients to the ovarian tissue.
3. Recruit and Mature Healthy Eggs:
Aid in the development and maturation of high-quality eggs.
These effects collectively contribute to improved ovarian function and potentially better fertility outcomes. This technique is gaining attention as a natural and efficient way to boost fertility by leveraging the body's own regenerative capabilities.
The process of Ovarian PRP (Platelet-Rich Plasma) involves several steps designed to ensure the safe and effective preparation and administration of PRP. Here’s a detailed overview:
Step-by-Step Process of Ovarian PRP
1
Consultation and Evaluation:
  • The patient undergoes a thorough medical evaluation, including a review of medical history, hormonal tests, and ultrasound assessments to determine ovarian reserve and overall reproductive health.
2
Blood Draw:
  • A sample of the patient’s blood is drawn, usually from a vein in the arm. The volume of blood collected can vary but typically ranges from 20 to 60 milliliters.
3
Preparation of PRP:
  • The blood sample is processed using a centrifuge, a machine that spins the blood at high speeds to separate its components. This process isolates the platelet-rich plasma from the other blood components (red blood cells and white blood cells).
  • The resulting PRP is a concentrated solution rich in platelets and growth factors essential for tissue repair and regeneration.
4
Activation of PRP:
  • In some protocols, PRP may be activated by adding substances like calcium chloride or thrombin to release growth factors more effectively.
5
Ultrasound-Guided Injection:
  • The PRP is injected into the ovaries using a fine needle. This procedure is performed under ultrasound guidance to ensure accurate placement of the PRP into the ovarian tissue.
  • Local anesthesia or mild sedation may be used to minimize discomfort during the injection.
6
Post-Procedure Monitoring:
  • After the injection, the patient is monitored for a short period to ensure there are no immediate adverse reactions. Most patients can return to normal activities shortly after the procedure.
  • Follow-up visits may be scheduled to monitor ovarian response through blood tests and ultrasound examinations.
7
Potential Repeat Treatments:
  • Depending on the patient’s response, additional PRP treatments may be recommended. The interval between treatments and the total number of sessions vary based on individual cases and treatment protocols.
Benefits
Ovarian PRP aims to improve ovarian function, increase the quality and quantity of eggs, and enhance fertility outcomes.
It is a minimally invasive procedure with a relatively short recovery time.
Considerations
The effectiveness of Ovarian PRP can vary among individuals. Factors such as age, ovarian reserve, and overall health play a significant role in the success of the treatment.
As with any medical procedure, there are risks involved, including infection, bleeding, and potential discomfort at the injection site.
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Summary
Ovarian PRP is a promising technique that leverages the body's natural regenerative capabilities to enhance ovarian function and improve fertility outcomes. By using the patient's own blood, this method reduces the risk of adverse reactions and offers a natural approach to reproductive health. However, it is important for patients to have realistic expectations and consult with a fertility specialist to determine if Ovarian PRP is suitable for their specific situation.
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